G-CAN 2022 EARLY CAREER INVESTIGATOR ABSTRACT SYMPOSIUM AWARD RECIPIENTS

G-CAN 2022 H. Ralph Schumacher Memorial Early Career Investigator Award Lecture

Concepcion Sanchez San Diego, US; David Gonzalez, Robert Terkeltaub, Mentors
Sustained xanthine oxidase inhibitor (XOI) treat to target (T2T) urate lowering therapy (ULT) rewires a tight inflammation protein interactome detected by quantitative multiplex serum proteomics.

SPARK (Select Presentation of Abstract Research Keynotes) Presenters

Sandy ElSayed, Irvine, US; Khaled Elsaid Mentor
Protein Phosphatase-2A regulates xanthine oxidase activity in macrophages and influx of inflammatory monocytes in a murine gout model.
Isidoro Cobo, PhD San Diego, US; Christopher Glass, Mentor
Epigenetic activation of the lysosomal biogenesis program by collaborative binding with TFEB is required for appropriate response of macrophages to monosodium urate crystals.
Edoardo Cipolletta, MD Nottingham, UK; Abhishek Abhishek, Mentor
Risk of venous thromboembolism after gout flares.
Orsolya Gaal, PhD Cluj-Napoca, Romania; Leo Joosten, Mentor
Gout-associated SNP at the IL1RN-IL1F10 region is functionally linked to altered cytokine production in PBMCs of patients with gout and controls.
Panagiota Drivelegka, MD, PhD Gothenburg, Sweden: Lennart Jacobsson, Mentor
Allopurinol use and risk of acute coronary syndrome in patients with incident gout: a population-based study in Sweden.
Jean Liew, MD Boston, US; Tuhina Neogi, Mentor
The association of intra-articular mineralization on CT and radiographic chondrocalcinosis with location-specific cartilage loss on MRI in knee OA: The Multicenter Osteoarthritis Study.
Leanne Chen, Auckland, NZ; Nicola Dalbeth, Mentor
Changes in tophus composition during urate-lowering therapy: A dual energy CT study.

EARLY CAREER INVESTIGATOR ABSTRACT PRESENTERS

Florian A. Huber, MD Zurich, Switzerland; Jürg Hodler, Mentor
Increased sensitivity and specificity of crystal detection in novel photon-counting-detector computed tomography compared to energy-integrating-detector computed tomography.
Georgiana Cabău, MD, Cluj-Napoca, Romania; Leo Joosten, Mentor
Serum proteome profiling in gout and asymptomatic hyperuricemia reveals common and persistent inflammatory alterations.
Antonella Adinolfi, MD Milan, Italy; Georgios Filippou, Mentor
Assessing relevant joints for monitoring CPPD diseases by imaging: A systematic literature review and a meta-analysis by the OMERACT Ultrasound – CPPD subgroup.
Silvia Sirotti, MD Milan, Italy; Georgios Filippou; Mentor
The OMERACT validation process of Ultrasound for assessment of CPPD: What’s next? A scoring for CPPD extent!
Tate Johnson, MD Omaha, US; Ted Mikuls, Mentor
Poor serum urate control is a driver of excess cardiovascular risk in patients with gout.
Medeea Badii Cluj-Napoca, Romania; Leo Joosten, Mentor
Comparison of IL1 receptor antagonist and interferon inducible gene signatures of urate-treated PBMCs and primary cells from patients with hyperuricemia and gout.
Tom Niessink, Enschede, The Netherlands; Tim Jansen, Mentor
Integrating Raman spectroscopy with polarized light microscopy leads to a higher certainty of diagnosis in crystallopathies.
Giovanni Pacini, MD Florence, Italy; Georgios Filippou, Mentor
Sonoanatomy of CPPD: correlation of ultrasonographic and anatomical findings in CPP Deposition. A study of the EULAR “anatomy for imaging” study group.
Kaifeng Guo, PhD Shanghai, China; Haibing Chen, Mentor
Serum metabolomics study of patients with asymptomatic hyperuricemia and gout using liquid chromatography–mass spectrometry.
Dorsa Maher, Adelaide, Australia; Michael Wiese, Mentor
#Urate-lowering therapy induced gout flares: a systematic review and network meta-analysis.
Lesley Jackson, MD Birmingham, US; Maria Danila, Mentor
Outpatient follow-up after an emergency department visit for acute gout flare.
Rachael Flood Dublin, Ireland; Ronan Mullen, Mentor
Pulmonary vascular dysfunction occurs in association with hyperuricaemia: Assessment by a novel non-invasive measurement of pulmonary pulse wave transit time.